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To calculate the particular methylation list private investigator, we permit the proportion Ri=p(Nimet)s(Niunmet)=(NimetNmet)(NiunmetNunmet). Since Nmet?= Nunmet?= 12,584, we've got Ri=NimetNiunmet=(fipi��(fipi))(fi(1?pi)��(fi(1?pi)))=pi(1-pi)?(��fi?��(fipi))��(fipi). Since �� fi?= 1, as well as ��(fipi) may be the anticipated typical methylation stage Ep for all CGs in the genome (many of us used

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