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TLR signalling by means of MyD88-ASK1 (apoptosis transmission regulating kinase-1) stimulates p38 [51]. In the course of epidermis differentiation, the particular TLR2-ASK-1-p38 procede raises the manufacture of LL-37 [52]. As a result, there exists an important epidermis TLR2 path managing cathelicidin phrase. KLK5-mediated proteolysis ultimately tunes the particular neurological action involving

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