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As proven within Fig. 1b in which pVHL term had been covered up within the A549-sh-VHL tissues. Given that A549 cells convey the two HIF-1�� and HIF-2�� and also lack of pVHL stabilizes HIF-�� [24], many of us determined the expression of HIF-1�� along with HIF-2�� inside A549-sh-VHL cellular material. Because demonstrated inside Fig. 1B, knockdown involving pVHL stabilized both HIF-1�� along with

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